• TeamResearch

Bacteriophages safely reduce Salmonella contamination in pet food and raw pet food ingredients

Updated: May 9

DATE 2016

CITATION: Soffer N, Abuladze T, Woolston J, Li M, Hanna LF, Heyse S, Charbonneau D, Sulakvelidze A. Bacteriophage. 2016 Aug 5;6(3):e1220347


LINK: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056775/


ABSTRACT:

Contamination of pet food with Salmonella is a serious public health concern, and several disease outbreaks have recently occurred due to human exposure to Salmonella tainted pet food. The problem is especially challenging for raw pet foods (which include raw meats, seafood, fruits, and vegetables). These foods are becoming increasingly popular because of their nutritional qualities, but they are also more difficult to maintain Salmonella-free because they lack heat-treatment. Among various methods examined to improve the safety of pet foods (including raw pet food), one intriguing approach is to use bacteriophages to specifically kill Salmonella serotypes. At least 2 phage preparations (SalmoFresh® and Salmonelex™) targeting Salmonella are already FDA cleared for commercial applications to improve the safety of human foods. However, similar preparations are not yet available for pet food applications. Here, we report the results of evaluating one such preparation (SalmoLyse®) in reducing Salmonella levels in various raw pet food ingredients (chicken, tuna, turkey, cantaloupe, and lettuce). Application of SalmoLyse® in low (ca. 2–4×106 PFU/g) and standard (ca. 9×106 PFU/g) concentrations significantly (P < 0.01) reduced (by 60–92%) Salmonella contamination in all raw foods examined compared to control treatments. When SalmoLyse®-treated (ca. 2×107 PFU/g) dry pet food was fed to cats and dogs, it did not trigger any deleterious side effects in the pets. Our data suggest that the bacteriophage cocktail lytic for Salmonella can significantly and safely reduce Salmonella contamination in various raw pet food ingredients.

ABOUT

This website is a labor of love brought to you by the volunteers at Paws For Change. Our goal is to put together links to published research studies, articles, books, and other media which have influenced our approach to feeding diets that include fresh and raw foods. We encourage everyone to research further to gain a fuller understanding of any controversies or debates involved. It is a growing collection and we welcome you to use the submission form below if you have studies you'd like to suggest be included here.

Submit A Study
Paws For Change (1).png

 Brought to you by